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  • Title: Use of alendronate in the treatment of vitamin D intoxication in infants.
    Author: Hatun S, Cizmecioğlu F.
    Journal: Turk J Pediatr; 2005; 47(4):373-5. PubMed ID: 16363349.
    Abstract:
    Vitamin D intoxication remains a challenging problem due to lack of an efficient treatment. Bisphosphonates, inhibitors of osteoclast-mediated bone resorption, however, have been proposed as a safe and effective alternative in the treatment of vitamin D intoxication. We present here two infants with vitamin D intoxication who were successfully treated with alendronate. We propose that oral alendronate is an alternative to intravenous bisphosphonates in the treatment of vitamin D intoxication in infancy.
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