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  • Title: A prospective comparison of clamping the drain or post-operative salvage of blood in reducing blood loss after total knee arthroplasty.
    Author: Tsumara N, Yoshiya S, Chin T, Shiba R, Kohso K, Doita M.
    Journal: J Bone Joint Surg Br; 2006 Jan; 88(1):49-53. PubMed ID: 16365120.
    Abstract:
    We undertook a prospective, randomised study in order to evaluate the efficacy of clamping the drains after intra-articular injection of saline with 1:500 000 adrenaline compared with post-operative blood salvage in reducing blood loss in 212 total knee arthroplasties. The mean post-operative drained blood volume after drain clamping was 352.1 ml compared to 662.3 ml after blood salvage (p < 0.0001). Allogenic blood transfusion was needed in one patient in the drain group and for three in the blood salvage group. Drain clamping with intra-articular injection of saline with adrenaline is more effective than post-operative autologous blood transfusion in reducing blood loss during total knee arthroplasty.
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