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  • Title: beta-Carotene and alpha-tocopherol are synergistic antioxidants.
    Author: Palozza P, Krinsky NI.
    Journal: Arch Biochem Biophys; 1992 Aug 15; 297(1):184-7. PubMed ID: 1637180.
    Abstract:
    The possibility of a cooperative interaction between fat-soluble antioxidants is examined in a membrane model. A combination of beta-carotene and alpha-tocopherol results in an inhibition of lipid peroxidation significantly greater than the sum of the individual inhibitions. Our data provide the first evidence that beta-carotene can act synergistically with alpha-tocopherol as an effective radical-trapping antioxidant in membranes.
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