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  • Title: [Biologic therapy with anti-TNFα in spondyloarthritides and other autoimmune diseases].
    Author: Lapadula G.
    Journal: Reumatismo; 2005; 57(4 Suppl):22-9. PubMed ID: 16385352.
    Abstract:
    OBJECTIVE: To evaluate the efficacy of the anti-TNFα (Tumor Necrosis Factor alpha) drugs in a variety of pathologic conditions such as psoriatic arthritis, undifferentiated entheso-arthritides, chronic inflammatory bowel diseases, adult onset Still's disease, Behcet disease. METHODS: Review of all published studies evaluating the efficacy of these drugs (mainly infliximab and etanercept, adalimumab to a lesser degree) on the above diseases. RESULTS: Results are reported for each pathologic condition. Both drugs showed to be very efficacious in all the above conditions, except Crohn disease where etanercept does not seem adequate. CONCLUSIONS: Both drugs work extremely well, even though comparison between infliximab and etanercept efficacy cannot be performed, due to the lack of a direct comparison.
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