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  • Title: HacA-independent induction of chaperone-encoding gene bipA in Aspergillus niger strains overproducing membrane proteins.
    Author: Davé A, Jeenes DJ, Mackenzie DA, Archer DB.
    Journal: Appl Environ Microbiol; 2006 Jan; 72(1):953-5. PubMed ID: 16391143.
    Abstract:
    Transcription of two unfolded protein response genes, hacA and bipA, was examined in Aspergillus niger strains overproducing membrane proteins. Despite elevated bipA mRNA levels, no 5'-truncated hacA transcript was detected, raising the possibility of a hacA-independent induction of bipA mRNA under the stress of membrane protein overproduction in A. niger.
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