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  • Title: The Morita-Baylis-Hillman adducts of beta-aryl nitroethylenes with other activated alkenes: synthesis and anticancer activity studies.
    Author: Dadwal M, Mohan R, Panda D, Mobin SM, Namboothiri IN.
    Journal: Chem Commun (Camb); 2006 Jan 21; (3):338-40. PubMed ID: 16391753.
    Abstract:
    The Morita-Baylis-Hillman (MBH) adducts of beta-aryl nitroethylenes with methyl vinyl ketone (MVK) and acrylate, formed in moderate to good yield when mediated by imidazole/LiCl in THF at room temperature, inhibit HeLa cell proliferation by binding to tubulin.
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