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  • Title: Intrauterine lignocaine as an anaesthetic during endometrial sampling: a randomised double-blind controlled trial.
    Author: Hui SK, Lee L, Ong C, Yu V, Ho LC.
    Journal: BJOG; 2006 Jan; 113(1):53-7. PubMed ID: 16398772.
    Abstract:
    OBJECTIVE: To evaluate the effectiveness of intrauterine lignocaine as an anaesthetic during endometrial sampling. DESIGN: Prospective, randomised, double-blind, placebo-controlled trial. SETTING: Outpatient gynaecological minor operation unit in a public hospital. POPULATION: Two hundred premenopausal women scheduled for endometrial sampling because of abnormal uterine bleeding. METHODS: Transcervical intrauterine instillation of 5 mL of 2% lignocaine or 5 mL of normal saline before performing endometrial sampling with vacuum aspirator. MAIN OUTCOME MEASURES: Evaluation of pain associated with the procedure using a visual analogue scale. RESULTS: The use of intrauterine lignocaine reduced pain during suction curettage in endometrial sampling. CONCLUSIONS: Transcervical instillation of lignocaine reduced pain during endometrial sampling.
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