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  • Title: Genomic regulation of Hox collinearity.
    Author: Freitas R, Cohn MJ.
    Journal: Dev Cell; 2006 Jan; 10(1):8-9. PubMed ID: 16399073.
    Abstract:
    During vertebrate limb development, Hoxd genes are transcribed in two temporal phases; an early wave controls growth and polarity up to the forearm and a late wave patterns the digits. In this issue of Developmental Cell, Tarchini and Duboule (2006) report that two opposite regulatory modules direct early collinear expression of Hoxd genes.
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