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  • Title: Central neurocytoma: report of two cases.
    Author: Borges G, Pereira HC, Carelli EF, Fernandes YB, Bonilha L, Roma MF, Zanardi VA, Netto JR, Schenka AA, Queiroz LS.
    Journal: Arq Neuropsiquiatr; 2005 Dec; 63(4):1084-9. PubMed ID: 16400433.
    Abstract:
    INTRODUCTION: Central neurocytomas are rare neuroectodermal tumors believed to arise from the subependymal matrix of the lateral ventricles. CASE REPORTS: A 26-year-old woman and a 33-year-old man each had a large, heterogeneous, contrast enhancing mass in the lateral ventricles at the foramen of Monro causing bilateral hydrocephalus. The woman died after surgery, but the man is asymptomatic after three years. HISTOPATHOLOGY: Both tumors were composed of isomorphic rounded cells positive for synaptophysin, chromogranin and NSE, while some reacted for GFAP, vimentin and S-100 protein. Electron microscopy revealed neuropil-like tissue between cells, but synapses were rare.
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