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  • Title: Autologous peripheral blood stem cell transplantation for POEMS syndrome.
    Author: Kuwabara S, Misawa S, Kanai K, Kikkawa Y, Nishimura M, Nakaseko C, Cho RK, Hattori T.
    Journal: Neurology; 2006 Jan 10; 66(1):105-7. PubMed ID: 16401856.
    Abstract:
    Polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes syndrome is a rare multisystem disorder. Overproduction of vascular endothelial growth factor (VEGF) by plasmocytoma could be responsible for the symptoms. The authors treated four patients with high-dose chemotherapy and autologous peripheral blood stem cell transplantation. Within 6 months, symptoms associated with rapid normalization of serum VEGF levels improved.
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