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  • Title: The gene lin-3 encodes an inductive signal for vulval development in C. elegans.
    Author: Hill RJ, Sternberg PW.
    Journal: Nature; 1992 Aug 06; 358(6386):470-6. PubMed ID: 1641037.
    Abstract:
    The lin-3 gene is necessary for induction of the Caenorhabditis elegans vulva by the anchor cell. It encodes a molecule similar to epidermal growth factor and to transforming growth factor-alpha and acts through the epidermal growth factor receptor homologue let-23. Expression of lin-3 in the anchor cell stimulates vulval induction; lin-3 may encode the vulval inducing signal.
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