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Title: Sequence and variability of the 5.8S and 26S rRNA genes of Pneumocystis carinii. Author: Liu Y, Rocourt M, Pan S, Liu C, Leibowitz MJ. Journal: Nucleic Acids Res; 1992 Jul 25; 20(14):3763-72. PubMed ID: 1641341. Abstract: The sequence of the coding region of the rRNA operon of rat-derived Pneumocystis carinii has been completed, including the genes for 5.8S and 26S rRNA. These genes show homology to the rRNA genes of yeast, and an apparent group I self-splicing intron is present in the 26S rRNA gene. Like a similar intron in the 16S rRNA gene, this intron is in a phylogenetically conserved region. Variation in the 26S rRNA sequence was noted between P. carinii organisms isolated from two different sources.[Abstract] [Full Text] [Related] [New Search]