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  • Title: An SDF-1 trap for myeloid cells stimulates angiogenesis.
    Author: Ruiz de Almodovar C, Luttun A, Carmeliet P.
    Journal: Cell; 2006 Jan 13; 124(1):18-21. PubMed ID: 16413476.
    Abstract:
    In this issue of Cell, Grunewald et al. (2005) examine the role of hematopoietic cells in the formation of new blood vessels. They show that organ-specific expression of vascular endothelial growth factor (VEGF) is sufficient to mobilize and recruit hematopoietic cells from the bone marrow to the blood, but retention of the proangiogenic subpopulation of hematopoietic cells in peripheral organs requires an additional factor, stromal-derived factor 1 (SDF-1).
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