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  • Title: The derivatives of 3-(1H-benzikmidazole-2) propanoic acid synthesis and analgetic and anti inflammatory activity.
    Author: Ayalp A.
    Journal: Pak J Pharm Sci; 1989 Jan; 2(1):7-12. PubMed ID: 16414630.
    Abstract:
    Several derivatives of 3-(1H-benzimidazole-2) propanoic acid (Procodazol) were prepared using some aldehydes by the condensation reaction. The resulting products were lactam and acid derivatives. According to the spectral studies it was found that the hydrogen atoms of the 3-methylene group of 3-(1H-benzimidazole-2) propanoic acid take part in the reaction. 3-(2'-(Acetoxyphenyl) methylene)-2, 3-dihydro-1H-pyrrole (1, 2a) benzimidazole lone (3c) was found to possess some analgetic properties.
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