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  • Title: Mucinous eccrine adenocarcinoma of the periocular region.
    Author: Durairaj VD, Hink EM, Kahook MY, Hawes MJ, Paniker PU, Esmaeli B.
    Journal: Ophthalmic Plast Reconstr Surg; 2006; 22(1):30-5. PubMed ID: 16418662.
    Abstract:
    PURPOSE: To report 4 patients with mucinous eccrine adenocarcinoma of the periocular region. METHODS: Interventional case series of 4 patients with mucinous eccrine adenocarcinoma of the periocular region treated at 2 centers. RESULTS: Two patients with mucinous eccrine adenocarcinoma of the upper eyelid, 1 with mucinous eccrine adenocarcinoma of the lower eyelid, and 1 with mucinous eccrine adenocarcinoma of the eyebrow were included in this report. The lower eyelid lesion and the eyebrow lesion recurred after Mohs micrographic surgery. Both recurrent lesions were treated with Mohs micrographic surgery and postoperative adjuvant external-beam radiation therapy. The other 2 primary tumors were treated with wide local excision with frozen section control of margins and did not recur. The follow-up time after the most recent surgical procedure ranged from 8 to 17 months (median, 12 months). CONCLUSIONS: Mucinous eccrine adenocarcinoma is a rare ocular adnexal neoplasm that can involve the eyelid and periocular skin, can be locally invasive, and has a high risk of local recurrence despite Mohs surgery.
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