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  • Title: Normalization in quantitative [18F]FDG PET imaging: the 'body surface area' may be a volume.
    Author: Laffon E, Suárez K, Berthoumieu Y, Ducassou D, Marthan R.
    Journal: Phys Med Biol; 2006 Feb 07; 51(3):N47-50. PubMed ID: 16424575.
    Abstract:
    Non-invasive methods for quantifying [(18)F]FDG uptake in tumours often require normalization to either body weight or body surface area (BSA), as a surrogate for [(18)F]FDG distribution volume (DV). Whereas three dimensions are involved in DV and weight (assuming that weight is proportional to volume), only two dimensions are obviously involved in BSA. However, a fractal geometry interpretation, related to an allometric scaling, suggests that the so-called 'body surface area' may stand for DV.
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