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Title: Dibutyl phthalate, the bioactive compound produced by Streptomyces albidoflavus 321.2. Author: Roy RN, Laskar S, Sen SK. Journal: Microbiol Res; 2006; 161(2):121-6. PubMed ID: 16427514. Abstract: It was found that the bioactive compound, dibutyl phthalate, was produced by a new soil isolate Streptomyces albidoflavus 321.2. Once this active compound was recovered by ethyl acetate from the fermented broth, being possible to isolate 13.4 mg/l, it was purified by paper, silica gel column, thin layer and gas chromatography. Structure was determined by analysing UV, IR and GC-MS spectra. During analysis, such active compound showed strong activity against gram-positive and gram-negative bacteria, as well as unicellular and filamentous fungi. The antimicrobial activity of the compound was reversed by the amino acid proline. No acute toxicity was observed.[Abstract] [Full Text] [Related] [New Search]