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  • Title: Bullous hemorrhagic dermatosis occurring at sites distant from subcutaneous injections of heparin: three cases.
    Author: Perrinaud A, Jacobi D, Machet MC, Grodet C, Gruel Y, Machet L.
    Journal: J Am Acad Dermatol; 2006 Feb; 54(2 Suppl):S5-7. PubMed ID: 16427995.
    Abstract:
    Cutaneous side effects from heparin administration are rare and usually located at injection sites. We report 3 cases of intraepidermal hemorrhagic blisters occurring distant from sites of subcutaneous injections of heparin. A causative link is suggested by a temporal relationship between heparin introduction and onset of disease as well as exclusion of other causes, but the mechanism remains unknown.
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