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  • Title: One-step preparation of Hageman factor fragment concentrate.
    Author: Simonianová E.
    Journal: Biomed Chromatogr; 1992; 6(4):194-5. PubMed ID: 1643388.
    Abstract:
    The Hageman factor fragment (HFf) concentrate was prepared from acetone and dextran sulphate activated human plasma by chromatography on a CM-Sephadex column. The preparation was free of the main kallikrein inhibitors--Cl-inactivator, alpha 2-macroglobulin, antithrombin III and alpha 1-antitrypsin. The HFf concentrate can serve as an activator of prekallikrein in patient plasma.
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