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  • Title: Microwave-enhanced synthesis of new (-)-steganacin and (-)-steganone aza analogues.
    Author: Beryozkina T, Appukkuttan P, Mont N, Van der Eycken E.
    Journal: Org Lett; 2006 Feb 02; 8(3):487-90. PubMed ID: 16435866.
    Abstract:
    [reaction: see text]. A novel, microwave-enhanced, highly efficient protocol for the synthesis of hitherto unknown (-)-steganacin and (-)-steganone 7-aza analogues containing a 1,2,3-triazole ring has been presented. Microwave irradiation was found to be highly beneficial in promoting the Suzuki reaction and the 1,3-dipolar cycloaddition reaction to generate the highly strained medium-sized ring system of the title molecules.
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