These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
Pubmed for Handhelds
PUBMED FOR HANDHELDS
Search MEDLINE/PubMed
Title: Glucose-insulin-potassium infusion in acute myocardial infarction: a hemodynamic study. Author: Bergstra A, Svilaas T, van den Heuvel AF, van der Horst IC, Zijlstra F. Journal: Am Heart J; 2006 Feb; 151(2):345-51. PubMed ID: 16442897. Abstract: BACKGROUND: In this study, we investigated whether adjunction of glucose-insulin-potassium (GIK) infusion to primary percutaneous coronary intervention (PCI) affects hemodynamics in patients with an acute myocardial infarction. METHODS: Hemodynamic measurements were performed in a subset of patients (n = 81) in the GIPS 2, starting immediately after PCI and continued for 12 hours. RESULTS: Cardiac index values were stable in both groups. During the first measurements, diastolic pulmonary artery pressure and the pulmonary capillary wedge pressure (PCWP) were significantly higher in the non-GIK group (diastolic pulmonary artery pressure 15 +/- 5 vs 18 +/- 7 mm Hg, P = .028 and PCWP 14 +/- 6 vs 18 +/- 7 mm Hg, P = .030). There was a decrease in PCWP from 18 +/- 7 to 15 +/- 6 mm Hg in the non-GIK group during the first 6 hours, whereas the pressures remained at 14 +/- 6 mm Hg in the GIK group. This difference in pattern of change did not reach statistical significance in the analysis of the interaction of PCWP by GIK group (P = .065). CONCLUSIONS: Glucose-insulin-potassium infusion as adjunctive therapy to PCI in patients with acute myocardial infarction, without overt signs of heart failure, did not negatively affect hemodynamics.[Abstract] [Full Text] [Related] [New Search]