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  • Title: Chromosomal abnormalities in patients with azoospermia in Western Mexico.
    Author: Meza-Espinoza JP, Davalos-Rodríguez IP, Rivera-Ramírez H, Perez-Muñoz S, Rivas-Solís F.
    Journal: Arch Androl; 2006; 52(2):87-90. PubMed ID: 16443583.
    Abstract:
    In order to assess the frequency of chromosomal abnormalities in azoospermic males from western Mexico, we carried out a retrospective study in 227 patients. Forty-three (18.9%) cases with an abnormal karyotype were found. The most frequent chromosomal anomaly was 47,XXY, which was identified in 35 subjects (15.4%). In six cases (2.6%), structural aberrations were detected: two Robertsonian translocations [(45,XY,t(13;22)(p11;p11) and (45,XY,t(13;15)(p11;p11)], a Y;autosome translocation [46,XY,der(15)t(Y;15)(q12;p11)], and three mosaics [mos45,X/46,X,idic(Y)(q11)]. In general, these findings are in accordance with those from other surveys and confirm that the XXY aneuploidy is the most frequent chromosomal abnormality in azoospermic individuals.
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