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  • Title: Patch fluorometry: shedding new light on ion channels.
    Author: Zheng J.
    Journal: Physiology (Bethesda); 2006 Feb; 21():6-12. PubMed ID: 16443817.
    Abstract:
    Patch fluorometry has emerged as a new approach to the study of the structure-function relationship in membrane-embedded functional ion channels. Simultaneous fluorescent and electrical recordings are achieved from a small number of channels in a cell-free membrane patch, yielding high recording sensitivities. Further improvement of this approach should permit direct observation of the gating motion of a single-channel protein.
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