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  • Title: Intra-abdominal desmoid tumor following retroperitoneal lymph node dissection for testicular germ cell tumor.
    Author: Lawatsch EJ, Datta MW, Van Tuinen P, Sudakoff GS, Davis NB, Langenstroer P.
    Journal: Int J Urol; 2006 Jan; 13(1):84-6. PubMed ID: 16448440.
    Abstract:
    In the testicular cancer post-treatment setting a rapidly growing retroperitoneal mass leads to a differential diagnosis including recurrent germ cell tumor, residual mature teratoma, or sarcomatoid degeneration. We report the case of a 27-year-old man with a large abdominal mass occurring in the setting of a mixed germ cell tumor after radical orchiectomy with primary chemotherapy followed by retroperitoneal lymph node dissection. Surgical excision of this mass followed by pathological review revealed an intra-abdominal desmoid tumor. Fluorescence in situ hybridization (FISH) for isochromosome 12p failed to demonstrate a germ cell tumor origin. This is the fourth such case of an intra-abdominal desmoid tumor after retroperitoneal lymph node dissection for testicular cancer in the urologic literature. This case highlights the need for careful consideration of a desmoid tumor when a rapidly growing spindle cell tumor is encountered in a post-treatment testis cancer patient.
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