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  • Title: Palindromic morphea: multiple recurrence of morphea lesions in a case of systemic sclerosis.
    Author: Mizutani H, Tanaka H, Okada H, Mizutani T, Shimizu M.
    Journal: J Dermatol; 1992 May; 19(5):298-301. PubMed ID: 1644954.
    Abstract:
    We report an unusual scleroderma case. A 45-year-old woman had recurrent morphea lesions over 10 times in 6 years. She had had preceding inactive systemic scleroderma. New morphea lesions developed cyclically on various portions of her body and improved within 2 years. Interestingly, new lesions have developed on once involved skin as well as uninvolved skin. No exacerbation of systemic scleroderma was induced by outbreaks of new morphea lesions. We could not find a similar case in the literature and named it "Palindromic morphea" because of its unique clinical course. D-penicillamine treatment had a limited effect. Minimal oral prednisolone (5 mg/day) completely suppressed the multiple recurrence of the morphea lesions and enhanced improvement of the sclerosis.
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