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  • Title: Novel skeleton terpenes from Celastrus hypoleucus with anti-tumor activities.
    Author: Wang KW, Mao JS, Tai YP, Pan YJ.
    Journal: Bioorg Med Chem Lett; 2006 Apr 15; 16(8):2274-7. PubMed ID: 16455245.
    Abstract:
    Celahypodiol 1, an unusual 17-membered carbon diterpenoid with a novel skeleton, and a new triterpenoid 12-oleanene-3beta,6alpha-diol 2, together with four known compounds furreginol 3, suigol 4, 20(30)-lupene-3beta, 29-diol 5, and 20(29)-lupene-1beta,3beta-diol 6, were isolated from the stalks of Celastrus hypoleucus (Oliv.) Warb. Their structures were established by means of spectroscopic analysis, including 2D NMR. The new compounds exhibited anti-tumor activities against a panel of human tumor cell lines.
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