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  • Title: Diazipine, a novel photoaffinity probe for dihydropyridine receptors of calcium channels.
    Author: Taki M, Nakayama H, Kanaoka Y.
    Journal: FEBS Lett; 1991 Jun 03; 283(2):259-62. PubMed ID: 1646123.
    Abstract:
    A new 1,4-dihydropyridine photoaffinity ligand, [3H]diazipine, has been assessed by binding and photolabeling, and compared with a currently used [3H]azidopine. [3H]Diazipine reversibly binds to skeletal muscle Ca2+ channels with a similar affinity to [3H]azidopine, but [3H]diazipine labels the channel two times more efficiently and no release of the incorported amount is observed after dithiothreitol treatment.
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