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  • Title: [Sox family regulate chondrogenesis].
    Author: Akiyama H.
    Journal: Clin Calcium; 2006 Feb; 16(2):368- 72. PubMed ID: 16465043.
    Abstract:
    Recent studies reveal that Sox family play crucial roles in cell lineage determination and cell differentiation during embryogenesis. In vitro analyses of type II collagen gene strongly suggested that Sox5, 6, and 9 are involved in cartilage-specific expression of type II collagen gene. Indeed, mouse genetics approaches clearly indicate that these Sox family transcription factors are essential for chondrogenesis.
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