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  • Title: Orientation of the haems of the ubiquinol oxidase:O2 reductase, cytochrome bo of Escherichia coli.
    Author: Salerno JC, Ingledew WJ.
    Journal: Eur J Biochem; 1991 Jun 15; 198(3):789-92. PubMed ID: 1646721.
    Abstract:
    The orientation of the two haems of the Escherichia coli ubiquinol oxidase:O2 reductase, cytochrome bo, has been determined by electron paramagnetic resonance studies on oriented multilayer preparations of cytoplasmic membrane fragments. The enzyme contains a low-spin b-like haem and a high-spin b-like haem, designated cytochromes b and o respectively. Both haems are oriented with their planes perpendicular to the membrane plane, further extending the catalogue of structural and functional similarities between this enzyme and the mammalian cytochrome c oxidase, cytochrome aa3.
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