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  • Title: [Inflammatory type of malignant fibrous histiocytoma in the anterior mediastinum--a case report].
    Author: Kasahara D, Masuda R, Tanaka I, Inoue M, Takemura T.
    Journal: Nihon Kyobu Geka Gakkai Zasshi; 1991 Mar; 39(3):366-72. PubMed ID: 1646847.
    Abstract:
    A 58-year-old female was admitted to our hospital with a complaint of anterior chest tumor, fever of unknown origin and anemia. Chest X-ray films and chest CT scans revealed a large tumor in the anterior mediastinum, there were strong inflammatory reactions in laboratory studies. The tumor was resected with a part of the rt anterior chest wall. The partial resection of the upper and middle lobe of the rt lung and the pericardium which were invaded of the tumor were performed. Postoperative course was uneventful and body temperature went down. Inflammatory reaction and anemia got also improved. In histological findings, both rounded histiocyte-like and spindled fibroblast-like tumor cells were arranged in a random or haphazard fashion and showed a storiform pattern. And there was a collection of xanthoma-like foamy cells and invasive inflammatory cells. So the histological diagnosis was inflammatory type of MFH. As far as we investigated, this case was the 23rd mediastinal MFH in the world literature.
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