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  • Title: CuI-Catalyzed tandem intramolecular amidation using gem-dibromovinyl systems.
    Author: Yuen J, Fang YQ, Lautens M.
    Journal: Org Lett; 2006 Feb 16; 8(4):653-6. PubMed ID: 16468734.
    Abstract:
    [reaction: see text] Imidazoindolones are present as the key structural motif in the family of antifungals, fumiquinazolines, and the antagonist asperlicin. The first example of a CuI-catalyzed tandem intramolecular amidation forming substituted imidazoindolones from readily accessible ortho gem-dibromovinylanilines is described.
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