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  • Title: Rewritable DNA microarrays.
    Author: Schofield WC, McGettrick J, Bradley TJ, Badyal JP, Przyborski S.
    Journal: J Am Chem Soc; 2006 Feb 22; 128(7):2280-5. PubMed ID: 16478182.
    Abstract:
    Thiol-terminated single-stranded deoxyribonucleic acids (ssDNA) can be immobilized onto pulsed plasma deposited poly(allylmercaptan) surfaces via disulfide bridge chemistry and are found to readily undergo nucleic acid hybridization. Unlike other methods for oligonucleotide attachment to solid surfaces, this approach is shown to be independent of substrate material or geometry, and amenable to highly efficient rewriting.
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