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  • Title: [Alteration in respiratory enzyme system of myocardial mitochondria during reperfusion injury].
    Author: Yue P.
    Journal: Zhonghua Xin Xue Guan Bing Za Zhi; 1991 Feb; 19(1):36-8, 64. PubMed ID: 1647940.
    Abstract:
    Myocardial hypoxia and reperfusion injury models were made on isolated rabbit hearts. Myocardial mitochondria were isolated. The activities of succinate dehydrogenase and cytochrome oxidase as well as cytochrome contents were studied. Comparing with normal controls, no significant alteration in succinate dehydrogenase activity and cytochrome contents were observed in hypoxia group while cytochrome oxidase activity compensative increased. In reperfusion group, the activities of the two respiratory enzymes and the contents of cytochromes decreased significantly, suggesting that reperfusion injury resulted in severe damage in respiratory enzyme system of myocardial mitochondria.
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