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  • Title: Immunity to transmissible (coronaviral) enteritis of turkeys (bluecomb).
    Author: Pomeroy BS, Larsen CT, Deshmukh DR, Patel BL.
    Journal: Am J Vet Res; 1975 Apr; 36(4 Pt 2):553-5. PubMed ID: 164801.
    Abstract:
    Turkey flocks recovering from natural and laboratory induced coronaviral enteritis developed lifelong immunity. Virus neutralization tests indicated that neutralization capacity of serums from recovered turkeys was low. One-way cross challenge test using turkeys inoculated with various bluecomb isolates revealed close antigenic relationship or antigenic identity among bluecomb isolates. The controlled application of intestinal preparations containing coronavirus as a vaccination procedure had value in developing active lasting immunity but it has limitations in areas that are attempting to eliminate the disease by a depopulation program. Killed vaccines injected parenterally did not produce a detectable immunity.
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