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  • Title: Beta1 adrenergic receptor polymorphisms Arg389Gly and Ser49Gly in the Amerindian and Mestizo populations of Mexico.
    Author: Fragoso JM, Rodríguez-Pérez JM, Pérez-Vielma N, Martínez-Rodríguez N, Vargas-Alarcón G.
    Journal: Hum Biol; 2005 Aug; 77(4):515-20. PubMed ID: 16485781.
    Abstract:
    The beta1 adrenergic receptor genotypes (Ser49Gly and Arg389Gly) were determined in 190 individuals from 3 Mexican populations. Mestizos and Teenek present the highest frequencies for the *Arg allele and the lowest frequencies for the *Gly allele (Arg389Gly) compared to European, Asian, and African populations. Mayos present the highest frequency for the *Gly allele. The knowledge of the distribution of these alleles could help define the significance of these polymorphisms as genetic susceptibility markers in Amerindian populations.
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