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  • Title: [Profile-effect on quality control of Houttuynia cordata injection].
    Author: Lu HM, Liang YZ, Qian P.
    Journal: Yao Xue Xue Bao; 2005 Dec; 40(12):1147-50. PubMed ID: 16496683.
    Abstract:
    AIM: To find corresponding relationship between the fingerprint of Houttuynia cordata injections from different factories and their effects. METHODS: Houttuynia cordata injections from six different factories were determined by gas chromatography (GC) and gas chromatography-mass spectra (GC-MS), and GC fingerprints were classified by hierarchical clustering. The anti-inflammatory activity of Houttuynia cordata injections was characterized through the rat pleurisy model induced by carrageenin and the mice ear edema model by dimethylbenzene. RESULTS: The anti-inflammatory effect of the injections from the first class factories on the two model was significant, while those from the second class not. GC-MS analysis result indicated that main effect compounds in Houttuynia cordata injections are methyl n-nonyl ketone, decanoylacetaldehyde, lauryl aldehyde, capryl aldehyde, beta-pinene, beta-linalool, 1-nonanol, 4-terpineol, alpha-terpineol, bornyl acetate, n-decanoic acid and acetic acid, geraniol ester etc. CONCLUSION: There is corresponding relationship between the fingerprint of Houttuynia cordata injections and effect to a certain extent.
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