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  • Title: [Role of the cerebellum in the control of distal motor activities in patients with akinetic-rigid Parkinson disease].
    Author: Moretti R, Torre P, Antonello RM, Ukmar M, Cazzato G, Pizzolato G.
    Journal: Recenti Prog Med; 2005 Dec; 96(12):599-603. PubMed ID: 16496744.
    Abstract:
    Using f-MRI, we have studied the changes induced by the performance of a complex sequential motor task in the cortical areas of nine akinetic PD patients and compared to that of healthy volunteers. Compared with normal subjects, PD patients showed a reduction of activation of motor and SMA areas, an increase of activation of parietal areas and a bilateral activation of cerebellar hemispheres, which are likely to participate in the attempt to recruit parallel motor circuits in order to overcome the striatocortical defective loop.
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