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  • Title: Surgical and radiotherapy treatment of a spinal cord ependymoma in a dog.
    Author: Ueno H, Morimoto M, Kobayashi Y, Hizume T, Murayama N, Uzuka Y.
    Journal: Aust Vet J; 2006; 84(1-2):36-9. PubMed ID: 16498832.
    Abstract:
    A 4-year-old Beagle dog was presented for investigation of a left pelvic limb gait abnormality. Neurolocalisation indicated a lumbar (L2 to L5) spinal cord lesion. On magnetic resonance imaging (MRI), an intramedullary mass was demonstrated at L3. The mass was partially removed under general anaesthesia and a diagnosis of ependymoma was made on histological examination. The dog was treated with postoperative orthovoltage x-ray radiation (total dose; 44 Gy given in 11 fractions over a 4 week period) combined with low dose carboplatin (25 mg/m2). The dog was alive 16 months after surgery without further neurological deficits. No further tumour growth was detected on subsequent MRI evaluations.
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