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  • Title: Caminosides B-D, antimicrobial glycolipids isolated from the marine sponge Caminus sphaeroconia.
    Author: Linington RG, Robertson M, Gauthier A, Finlay BB, MacMillan JB, Molinski TF, van Soest R, Andersen RJ.
    Journal: J Nat Prod; 2006 Feb; 69(2):173-7. PubMed ID: 16499312.
    Abstract:
    A screening program aimed at discovering inhibitors of the bacterial type III secretion system identified the MeOH extract of the Caribbean sponge Caminus sphaeroconia as an active hit in the initial assay. Bioassay-guided fractionation of the crude extract led to the isolation of caminosides A (1) to D (4), a family of antimicrobial glycolipids. The structures of the three new caminosides B (2) to D (4) have been elucidated by spectroscopic analysis.
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