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Title: Dietary supplements of vitamins E and C and beta-carotene reduce oxidative stress in cats with renal insufficiency. Author: Yu S, Paetau-Robinson I. Journal: Vet Res Commun; 2006 May; 30(4):403-13. PubMed ID: 16502108. Abstract: Oxidative stress may contribute to the progression of chronic renal failure. In this study, cats with spontaneous renal insufficiency were fed a dry cat food supplemented with the antioxidants vitamins E and C, and beta-carotene for 4 weeks. When compared with healthy cats, cats with renal insufficiency had a tendency to oxidative stress. The antioxidant supplements significantly reduced DNA damage in cats with renal insufficiency as evidenced by reduced serum 8-OHdG and comet assay parameters. Therefore, supplements of vitamins E and C and beta-carotene as antioxidants may be beneficial to cats with renal disease.[Abstract] [Full Text] [Related] [New Search]