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  • Title: [Nervous system involvement in hemorrhagic fever with renal syndrome].
    Author: Iushchuk ND, Dekonenko EP, Karetkina GN, Kulagina GM, Makarova SA, Rumo FV, Bakulina ZE, Dzagurova TK, Berko AI, Shakhgil'dian SV, Tkachenko EA.
    Journal: Klin Med (Mosk); 2005; 83(12):65-8. PubMed ID: 16502729.
    Abstract:
    The authors of the article describe two cases of hemorrhagic fever with renal syndrome (HFRS) with prevalence of signs of nervous system involvement. The first case was a 40-year-old woman with moderate HFRS, who developed Guillain-Barre syndrome of axonal-demyelinating polyneuropathy. An important observation was the absence of hemorrhagic or renal syndrome; combined therapy including plasmapheresis was successful. The second case demonstrated polymorphism of HFRS clinical manifestations with prevalence of neurological symptoms, which consisted in encephalopathy and no renal failure signs; hemorrhagic syndrome was moderate. In both cases the diagnosis was confirmed by elevated titer of antibodies to HFRS virus, belonging to the group of hantaviruses.
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