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  • Title: Primary Gougerot-Sjögren syndrome: a dermatological approach.
    Author: Roguedas AM, Youinou P, Lemasson G, Pennec YL, Misery L.
    Journal: J Eur Acad Dermatol Venereol; 2006 Mar; 20(3):243-7. PubMed ID: 16503880.
    Abstract:
    Gougerot-Sjögren syndrome (GSS) is a chronic heterogeneous non-organ-specific autoimmune disease, encompassing a wide spectrum of clinical manifestations. It is characterized by a lymphocytic infiltration of the exocrine glands, also called epitheliitis, resulting in xerostomia and keratoconjunctivitis sicca. The skin can also be involved; for example, xerosis is a consequence of epitheliitis. Dermatological consequences of polyclonal reactivity are vasculitis and manifestations of B-cell proliferation vary from plasma cell infiltrates to B-cell lymphoma.
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