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  • Title: Prediction of pelvic inflammatory disease among young, single, sexually active women.
    Author: Ness RB, Smith KJ, Chang CC, Schisterman EF, Bass DC, Gynecologic Infection Follow-Through, GIFT, Investigators.
    Journal: Sex Transm Dis; 2006 Mar; 33(3):137-42. PubMed ID: 16505735.
    Abstract:
    OBJECTIVES: To assess prediction strategies for pelvic inflammatory disease (PID). STUDY DESIGN: One thousand one hundred seventy women were enrolled based on a high chlamydial risk score. Incident PID over a median of 3 years was diagnosed by either histologic endometritis or Centers for Disease Control and Prevention criteria. A multivariable prediction model for PID was assessed. RESULTS: Women enrolled using the risk score were young, single, sexually active, and often had prior sexually transmitted infections. Incident PID was common (8.6%). From 24 potential predictors, significant factors included age at first sex, gonococcal/chlamydial cervicitis, history of PID, family income, smoking, medroxyprogesterone acetate use, and sex with menses. The model correctly predicted 74% of incident PID; in validation models, correct prediction was only 69%. CONCLUSIONS: Our data validate a modified chlamydial risk factor scoring system for prediction of PID. Additional multivariable modeling contributed little to prediction. Women identified by a threshold value on the chlamydial risk score should undergo intensive education and screening.
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