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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: Polymerase chain reaction in miniaturized systems: big progress in little devices.
    Author: Spitzack KD, Ugaz VM.
    Journal: Methods Mol Biol; 2006; 321():97-129. PubMed ID: 16508068.
    Abstract:
    A critical need exists for advanced technologies that enable genomic-based DNA analysis to be performed with significantly higher throughput and at a significantly lower cost than is attainable with current hardware. Miniaturized polymerase chain reaction systems offer an attractive platform to address these needs, combining the ability to perform rapid thermocycling with a portable device format that can be inexpensively mass produced. We review recent efforts aimed at developing these next-generation systems and discuss some of the practical considerations involved in adapting this technology for routine laboratory use.
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