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  • Title: Crystallization and preliminary X-ray crystallographic analysis of osteoclast-stimulating factor.
    Author: Li M, Meng Z, Xu Y, Lou Z, Rao Z.
    Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun; 2005 Jan 01; 61(Pt 1):128-30. PubMed ID: 16508112.
    Abstract:
    Osteoclast-stimulating factor increases osteoclast formation and bone resorption through a cellular signal transduction cascade, possibly by its interaction with c-Src or related family members. Crystals of human osteoclast-stimulating factor were obtained by the hanging-drop vapour-diffusion method using ammonium sulfate as a precipitant. The crystals are primitive orthorhombic and belong to P222 or a related space group, with unit-cell parameters a = 38.1, b = 54.9, c = 64.7 A.
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