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  • Title: Pulmonary complications of infliximab therapy in patients with rheumatoid arthritis.
    Author: Ostör AJ, Chilvers ER, Somerville MF, Lim AY, Lane SE, Crisp AJ, Scott DG.
    Journal: J Rheumatol; 2006 Mar; 33(3):622-8. PubMed ID: 16511933.
    Abstract:
    We describe 5 patients with rheumatoid arthritis (RA) who developed pulmonary complications following infliximab therapy; 4 patients had preexisting usual interstitial pneumonia. As the pathophysiology of the pulmonary insult is unknown, we advise caution in the use of anti-tumor necrosis factor-alpha therapy in patients with RA with underlying lung disease of sufficient severity to withhold methotrexate treatment.
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