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  • Title: P.O.E.M.S. syndrome with complete recovery after treatment of a solitary plasmocytoma.
    Author: Broussolle E, Vighetto A, Bancel B, Confavreux C, Pialat J, Aimard G.
    Journal: Clin Neurol Neurosurg; 1991; 93(2):165-70. PubMed ID: 1652401.
    Abstract:
    The P.O.E.M.S. syndrome is a rare clinical entity that has been described mainly in Japan. It is characterized by a progressive polyneuropathy with raised CSF protein content, organomegaly, endocrinopathy, skin changes and plasma cell dyscrasia. We report a new documented case associated with a solitary plasmocytoma of the 12th thoracic vertebra. Immunopathological and ultrastructural studies of the peripheral nerve did not disclose any immune-specific changes. Surgery and radiation therapy of the plasmocytoma allowed a complete recovery, with a 5-year follow-up. This case report illustrates the need for serial full skeletal survey, including scintigraphy, in middle-aged patients with progressive polyneuropathy of obscure origin.
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