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  • Title: Use of botulinum toxin type A for the treatment of masseteric muscle hypertrophy.
    Author: Arikan OK, Tan FU, Kendi T, Koc C.
    Journal: J Otolaryngol; 2006 Feb; 35(1):40-3. PubMed ID: 16527016.
    Abstract:
    We investigated the effectiveness of botulinum toxin A intramuscular injection for the management of masseteric muscle hypertrophy. Five patients with masseteric muscle hypertrophy were treated with botulinum toxin A (Dysport, Beaufour Ipsen, France). Clinical photographs were obtained before and between 3 and 6 months after application. Four patients are pleased with their present facial appearance. However, one patient reported mild discomfort about his appearance. Neither local nor general adverse effects were noted. Botulinum toxin A is a safe, easy-to-use, and effective nonsurgical option in the management of masseteric muscle hypertrophy. Its use is associated with a high degree of patient and physician satisfaction.
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