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  • Title: Nano nickel oxide/nickel incorporated nickel composite coating for sensing and estimation of acetylcholine.
    Author: Shibli SM, Beenakumari KS, Suma ND.
    Journal: Biosens Bioelectron; 2006 Dec 15; 22(5):633-8. PubMed ID: 16527477.
    Abstract:
    Pure nickel electrodes can be used as biosensors especially for sensing and estimating acetylcholine neurotransmitter. In the present work, a good electrochemical sensor was developed by electroplating nano nickel oxide reinforced nickel on graphite substrate. The morphology of the working electrode surface was studied by using a scanning electron microscope (SEM). The electrochemical and biological performance of the modified electrode was characterized by polarization studies in different media. The present modified electrode showed good sensing performance with a response time as low as 8s during sensing and estimation of acetylcholine. The sensitivity of the modified electrode was 34.88 microA/(microM cm(2)).
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