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  • Title: Palladium-catalyzed direct arylation of simple arenes in synthesis of biaryl molecules.
    Author: Campeau LC, Fagnou K.
    Journal: Chem Commun (Camb); 2006 Mar 28; (12):1253-64. PubMed ID: 16538241.
    Abstract:
    Significant progress has been made in the direct arylation of simple arenes. A number of catalyst systems have been developed which enable the intramolecular direct arylation of aryl chlorides, bromides and iodides in high yield as well as conditions capable of achieving intermolecular direct arylation with simple arenes. This account describes recent progress by our group and others in the development of these reactions.
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